People with persistent smell deficits are more likely to develop brain imaging abnormalities suggestive of Parkinson’s disease, or be diagnosed with the disease, than those whose deficits return to normal on a subsequent smell test, according to data from a Phase 2 study. Deficits in two consecutive smell tests,…
Read more
Scientists have shed new light on the interaction of toxic apha-synuclein clumps — a hallmark of Parkinson’s disease — with microglia, the brain’s immune cells. This interaction was found to be mediated by RAGE, a protein at the surface of microglia, which promoted the release of inflammatory molecules from…
Servier is set to launch a Phase 1 clinical trial in healthy volunteers to investigate an LRRK2 inhibitor, developed in collaboration with Oncodesign, as a treatment for Parkinson’s disease. The trial, to start before the end of the year, follows the clearance of the Phase 1 clinical trial…
Older age at onset, a faster rate of disease progression, and severe cognitive impairment are key factors in poorer survival rates for people with Parkinson’s disease, a study that followed patients in northern China for 10 years found. Fatigue may also be an indicator of poorer survival, while physical exercise…
GT-02287, Gain Therapeutics’ experimental oral therapy, reduced the toxic alpha-synuclein protein clumps that characterize Parkinson’s disease in lab-grown nerve cells derived from patients with disease-causing mutations in the GBA1 gene, the company announced. The treatment also boosted the function of lysosomes, the cells’ recycling centers, which is…
For columnist Samantha Felder and other Parkinson’s patients with REM sleep behavior disorder, dreaming can quickly turn into a nightmare.
Visit the Parkinson’s News Today forums to connect with others in the Parkinson’s community.
Want to stay up to date on all the latest on Parkinson’s disease? Click the link below to find more news and information.
Becoming educated and informed about Parkinson’s is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your Parkinson’s journey.
There is no cure for Parkinson’s yet, but there are treatments that can help manage the disease. Learn more about current therapeutic approaches here.
Get regular updates to your inbox.
